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Action of Abiraterone 250 mg
Abiraterone (its active substance is Abiraterone 250mg) is the drug of the latest generation, intended for the treatment of prostate cancer. Abiraterone suppresses the activity of enzyme called CYP17. In its turn, CYP17 participates in the biosynthesis of androgens affecting the growth of tumor. A large amount of CYP17 is contained in the tissues of testicles, adrenal glands and prostate cancer cells.
Abiraterone reduces the level of androgens, thereby stopping the progression of disease.
During clinical trials and subsequent use of the drug, it was revealed that Abiraterone 250 mg maintains the patient’s life quality at a decent level, inhibits the growth of tumor, relieves pain and helps to improve the general condition and extend the patient’s life. It was established that the general survival rate of patients using Abiraterone, is much higher than in those who didn’t receive the treatment with this drug.
Manufacturer and generics of Abiraterone.
You should buy Abiraterone only from the manufacturer (or the high-quality generics). The drug has been developed and released by the company “Janssen Research & Development”. There are following high-quality generics: Abiraterone (“Ranbaxy”, India), XBIRA (“Cipla Ltd.”) and ABSTET (“Biocon Ltd.”)
Indications for use.
In some patients with prostate cancer, the tumor cells affect not only prostate but also the other body parts. This condition is called a metastatic (advanced) prostate cancer. Treatment variants for this kind of cancer usually include hormone therapy, operation, radiation therapy and chemotherapy.
Way of use
This drug is taken in combination with prednisone for the treatment of prostate cancer, which has spread to other body parts (after the failure of surgical treatment). Abiraterone belongs to the group of medications called androgen antagonists (testosterone blockers). Testosterone prevents prostate cancer from growing and replication. The drug acts by impeding the release of testosterone, thus delaying the growth of prostate cancer. Abiraterone must not be used by women or kids.
This drug acts by decreasing androgen production in the organism. Androgens are hormones that contribute to the cancer growth in the prostate gland.
This drug is intended for the men with an inoperable prostate cancer (after the failure of other medications).
Way of use.
Take 4 pills of Abiraterone 250 mg (1000 mg) once a day (2 hours after or 1 hour before meal). The drug should be taken in combination with prednisone (5 mg twice a day).
Age under 18. Patients with expressed liver and kidney dysfunction, hypokalemia, hypertension and adrenal insufficiency should take the drug with caution.