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The remedy Alectinib 150mg is a remedy for ingestion. The remedy Alectinib 150mg is developed for patients with non-small cell lung cancer whose tumors are defined as ALK-positive.
ALK-positive NSCLC is more common in young people, women, as well as non-smokers and few smokers. With a certain type of NSCLC – adenocarcinoma – the tumor in most cases is ALK-positive.
The remedy Alectinib 150mg is prescribed by an oncologist.
The remedy Alectinib 150mg showed activity against metastases in the brain, which confirms the ability of the remedy to penetrate into the brain tissue. The brain is protected by the blood-brain barrier, which is a network of closely connected cells lining the inner surface of the blood vessels of the brain and spinal cord. One way in which the blood-brain barrier prevents the effects of molecules on the brain is to actively remove them during a process called “active efflux” (outflow of substances from the cell or tissue). The system of active efflux (outflow) does not recognize Alectinib 150mg, due to which the remedy penetrates into the brain tissue and has a therapeutic effect.
There are no significant interactions of Alectinib 150mg with other remedies have been identified in clinical trials.
The doctor will tell you about the prescribed doses of Alectinib 150mg and other medications if you are prescribed a combined treatment.
Dosage and Administration of Alectinib 150mg.
It is recommended to take 600 mg of the remedy Alectinib 150mg (4 capsules) 2 times a day with meals. The capsules are swallowed whole, without opening them and not pouring out the contents.
If you missed the appointment, do not use the missed dose. The next capsule is taken on schedule.
Similarly, do not take an additional dose if you immediately vomit immediately after taking Alectinib 150mg. With the development of toxic effects, it is permissible to take 300-450 mg of Alectinib 150mg two times a day. You can change the dose of the remedy only with the permission of the doctor. When serious adverse reactions occur, treatment should be discontinued.
Before starting therapy, tell your doctor if you have:
The remedy adversely affects the formation of the fetus, so it cannot be taken by pregnant patients. Do not plan a conception during the treatment of Alectinib 150mg. Women of childbearing age are advised to use contraception during therapy and for another one week after it is completed. For men – during therapy and for another three months after its completion. If the remedy was prescribed during lactation, breastfeeding should be discarded.