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Pharmacological action of Ceritinib 150 mg
The active substance of the unique drug is Ceritinib. This kinase inhibitor impedes the development of cancer cells by means of blocking the mutagenic protein in the structure of tumor. According to the general researches, the size of tumor reduces.
This powerful drug is used for the treatment of (metastatic) non-small cell lung cancer.
Ceritinib 150 is an anti-cancer drug that impedes the growth and replication of tumor cells in the body.
Ceritinib 150 is intended for the treatment of non-small cell lung cancer.
Ceritinib 150 can be used only if your tumor has an abnormal epidermal growth factor receptor (EGFR) gene.
Ceritinib 150 can hurt a fetus. Regardless of your gender, you should use efficient contraceptives to avert pregnancy during the treatment and for a few months afterwards. Remember that the treatment with Ceritinib can lead to the congenital defects.
The use of Ceritinib can cause liver failure. Contact your physician immediately if you have right-sided-stomach pain, sickness, lack of appetite, extreme fatigue, bruises or hemorrhage, change in the color of urine, or jaundice.
Moreover, Ceritinib can triggers lung or cardiovascular disorders.
Mechanism of action
As the increased ALK gene is believed to play an important role in the development of tumor cells in ALK+ NSCLC, Ceritinib 150 aims at this abnormal gene. As an ALK inhibitor, Ceritinib 150 allows to decreased or delay the growth of tumor cells in people with this kind of cancer. However, Ceritinib 150 may also affect the normal cells, which can cause adverse effects.
The drug was researched in ALK+ metastatic NSCLC in two clinical trials to define if the medication was safe and efficient. One trial involved the patients using it as their first-line drug. The other trial considered the patients who were using Ceritinib 150 after getting the other targeted treatment.
Features of use of Ceritinib 150 mg
Ceritinib should be taken once day (at least 2 hours after the meal). The common single dose is 5 capsules. The patients with kidney/liver disorders should undergo the treatment under the medical supervision.