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Short instruction for use of Sunitinib 12,5mg.
Sunitinib is a capsule, intended for the oral intake. According to description, the main active substance of this drug is Sunitinib 12,5mg. According to the instructions, Sunitinib 12,5mg is also used for the treatment of gastrointestinal stromal tumors and neuroendocrine pancreas tumor with metastases (if the surgical intervention is impossible for various reasons). The drug affects by suppressing the receptors of tyrosine kinases, thereby making it impossible for them to participate in the growth of tumors, the development of blood vessels supplying the cancer cells with nutrients. Moreover, the drug prevents the formation of removed metastases.
In case of oral intake; the drug is rapidly absorbed in the gastrointestinal tract. The maximum blood concentration is achieved within two weeks of treatment. Therefore, according to the specialist opinions, six-week treatment cycle is reasonable. You should take a drug once a day for 4 consecutive weeks, and then take a 2-week break for the recovery of the body and testing the clinical data and blood count in the cancer patients.
Individual intolerance to the drug, pregnancy, breastfeeding, severe kidney/liver failure. Before using Sunitinib 12,5mg, you should take a blood clotting test, as the drug affects the genesis of vessels supplying the tumor with blood and can cause hemorrhage. Besides, Sunitinib isn’t used in the pediatric practice.
Side effects of Sunitinib 12,5mg.
The use of this drug can cause the side effects, similar to those of any other chemotherapy drugs. They include anemia, leukopenia and thrombocytopenia, symptoms of intoxication, hair loss, fever and chill. Patients with brain metastases can experience seizures, loss of consciousness or memory impairments (depending on the localization of tumor).