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Indications for use
The drug is used both for the treatment and prevention of diseases caused by pathologies of thrombus formation.
The list of indications includes:
Prevention of risks and recurrence of venous thromboembolism in patients after endoprosthesis; Prevention of risks of stroke and thromboembolism in patients with non-valvular atrial fibrillation, in case of availability of risk factors; Treatment of pulmonary embolism, deep vein thrombosis, and prevention of these diseases.
Instructions for use
The drug is taken orally without reference to food intake. If you miss a dose, you should immediately take a missed dose and then take the drug two times per day according to the original scheme. It depends on the existing pathology of the patient. The duration is set by your doctor depending on the individual indicators.
There is a number of pathological conditions in which the use of the drug is associated with additional risks: patients with conditions in which monotherapy or treatment with the use of two antiplatelet drugs is needed, should analyze the risk-benefit ratio, since the drug can cause bleeding. The drug is not recommended for patients with liver disease, with blood clotting disorders. While taking acetylsalicylic acid, the risk of bleeding increases in patients with acute coronary syndrome complicated by cardiac and non-cardiac diseases. If hemorrhagic complications are required, you should stop taking the drug and identify the source of blood loss and its relief. Long-term discontinuation of the drug prior to surgery increases the risk of thrombosis. The drug increases the risk of spinal and epidural hematomas, which can cause paralysis in patients, who take the drug in the implementation of epidural or spinal anesthesia, puncture of these segments and in patients with epidural catheter. The drug is taken with caution in case of interventions in subarachnoid or epidural space in the absence of adequate hemostasis. It is undesirable to replace Apixaban 5mg treatment with non-fractional heparin.
Apixaban 5mg during pregnancy
At present, there are no data on the risks and consequences of taking Apixaban 5mg during pregnancy. Therefore, due to the unpredictability of the consequences for the formation of the fetus, it is not recommended to take the drug during pregnancy. There is no confidence in the safety of the drug for babies, so breast-feeding should be stopped when you start taking the drug.