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Hepatitis B is a serious liver infection, caused by HBV. Some patients suffering from hepatitis B have a chronic form of illness. About 2 billion of people worldwide have suffered from hepatitis B. More than two million people in the USA have chronic hepatitis B. Most of them look healthy; however, you should know that hepatitis is a sexually transmitted disorder. Moreover, it can spread through the needles contaminated with infected blood. Pregnant women can transmit hepatitis to their children. This virus can’t spread through water, meal or accidental contact.
Tenofovir Alafenamide Fumarate is the generic of Vemlidy, manufactured by Gilead Sciences.
TAF belongs to the group of nucleotide reverse transcriptase inhibitors (NRTIs). It is intended the treatment of chronic HBV and HIV infection.
Even though Tenofovir Alafenamide 25 mg is considered quite safe and effective, and is now a keystone of HIV antiviral therapy, its use may cause renal toxicity and reduced BMD. For comparison, TAF has been demonstrated to improve antiviral effectiveness, increased delivery of TFV into peripheral blood mononuclear cells and lymphoid tissues, an enhanced barrier to resistance, and better safety profile. Increased renal safety can be explained by reduced blood concentrations of tenofovir, and consequently lower risk of bone and kidney damage. Due to the fact that HIV antiretroviral treatment is generally life-long, decreased toxicity and higher effectiveness results in better treatments outcomes and stricter adherence in the long term.
Hepatitis B is a virus affecting the liver. Most adult people suffering from it for a short term and get better soon. This form of diseases is known as acute hepatitis B. In some cases, the virus becomes chronic (it is referred to as chronic hepatitis B). With time, it can affect the liver. Children suffering from hepatitis B are at greater risk of developing chronic hepatitis B.
Currently, there are only brand medications available in the market for the treatment of this virus. Therefore, Natco has invented the new generic version which is more efficient, viable and accessible. The company has manufactured tenofovir alafenamide generic medication under the brand Tenofovir Alafenamide 25 mg in India.
According to the company’s records, Tenofovir Alafenamide 25 mg is developed under license from Medicines of Patent Pool (MPP) and Gilead Sciences. The medication shows comparable effectiveness with an increased renal and bone safety profile in comparison with the previous version of tenofovir.