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Indications for Zejula 100 mg:
Zejula 100 mg is intended for the targeted therapy of women suffering from some kinds of ovarian, fallopian tube and peritoneal cancers, whose cancer has returned after receiving chemotherapy.
Zejula is a PARP inhibitor, used for the therapy of adults suffering from ovarian cancer.
Manufactured by the American drug company “Tesaro”, Zejula was approved by the FDA for the treatment of recurrent epithelial ovarian, peritoneal or fallopian tube cancer in 2017.
Reasons and symptoms of ovarian cancer
Ovarian cancer is marked by pathological growth of malignant tumors developing in the cells that cover the ovaries or fallopian tubes.
Ovarian cancer is the fifth-most common reason for cancer-related death among females. The signs of this disease include bloating, pain in the pelvis, swollen stomach and lack of appetite.
More than 20.000 new cases of ovarian cancer are registered annually in the USA, while about 65.000 people receives this diagnosis every year in Europe.
Niraparib (an active substance in Zejula 100 mg) acts by inhibiting the action of PARP-1 and PARP-2 – poly (ADP-ribose) polymerase – which restore the affected DNA in cells during their replication. Thus, the damaged DNA in tumor cells can’t be restored, which results in the death of tumor cells.
Zejula 100 mg should be taken after the platinum-based chemotherapy, when the cancer is reducing or has entirely disappeared.
How to use Zejula 100 mg?
Zejula 100 mg should be taken orally once a day. The common dosage is 300 mg a day. Swallow the tablets whole instead of breaking or chewing it. In case you skipped the pill, don’t take the double dose to compensate for a missed dose. If the drug caused vomiting, avoid taking another dose. Just take the next dose in due time. Inform your doctor if you have problems swallowing the drug.
Each pill contains 100 mg of active substance, which means that you’ll have to take several pills to get the necessary dose. It is essential to ensure that you take the right amount of drug each time. Always follow the doctor’s prescriptions.
The drug Zejula 100 mg has a lot of adverse effects, such as: sickness/ vomiting, exhaustion and blockage.
This medication can be used by the lactating women.